All ASC CPT codes
ASC Surgical · CPT/HCPCS

CPT 67221

Ocular photodynamic ther

CPT 67221 at a glance

Code
67221
Code type
CPT/HCPCS
Short descriptor
Ocular photodynamic ther
Category
ASC Surgical
ASC payment status
Payable in an ASC (surgical)
CMS addendum
AA (Surgical)
Typical setting
Ambulatory surgery center (POS 24); also commonly performed in an office or clinic (POS 11).

What is CPT code 67221?

CPT 67221 is a CPT/HCPCS procedure code. Its official CMS short descriptor is "Ocular photodynamic ther". In the ASC context it is grouped under ASC Surgical.

Is CPT 67221 payable in an ambulatory surgery center (ASC)?

CPT 67221 appears on Medicare's ASC Covered Procedures List (CMS Addendum AA), so Medicare reimburses it when the surgery is performed in a certified ambulatory surgery center.

Where is CPT 67221 typically performed?

Ambulatory surgery center (POS 24); also commonly performed in an office or clinic (POS 11).

Which specialties use CPT 67221?

CPT 67221 is most associated with Ophthalmology.

Specialties that use this code

Reference information compiled from the CMS April 2026 ASC payment addenda (AA, BB, EE). Codes, descriptors, and ASC payment status change with each CMS update. This is a coding reference, not billing, coding, or legal advice. Always verify against the current CMS addenda and individual payer policy before billing. CPT is a registered trademark of the American Medical Association.

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