CPT 78121
Red cell mass multiple
CPT 78121 at a glance
- Code
- 78121
- Code type
- CPT/HCPCS
- Short descriptor
- Red cell mass multiple
- Category
- ASC Ancillary
- ASC eligibility
- ASC-eligible (ancillary)
- Typical setting
- Ambulatory surgery center (POS 24) or hospital outpatient department (POS 22).
- Medicare ASC rate
- $299.90 national · 2026Q2
What is CPT code 78121?
CPT 78121 is a CPT/HCPCS procedure code. Its official short descriptor is "Red cell mass multiple". In the ASC context it is grouped under ASC Ancillary.
Is CPT 78121 eligible in an ambulatory surgery center (ASC)?
CPT 78121 is an ancillary service that can be provided in the ASC setting when it supports a surgical procedure.
Where is CPT 78121 typically performed?
Ambulatory surgery center (POS 24) or hospital outpatient department (POS 22).
What is the Medicare ASC payment rate for CPT 78121?
The national Medicare ASC payment rate for CPT 78121 is $299.90 (CMS ASC Payment System, 2026Q2). This is the national, unadjusted amount published by CMS; the amount an individual ambulatory surgery center is paid is adjusted for local wage index and may differ. It reflects Medicare's facility payment only and does not include the surgeon's professional fee.
Which specialties use CPT 78121?
CPT 78121 is most associated with Diagnostic Radiology.
Reference information about ASC eligibility and typical procedure setting. Codes, descriptors, and ASC-eligibility status change over time. This is a coding reference, not billing, coding, or legal advice. Always verify against current guidance and individual payer policy before scheduling or billing. CPT is a registered trademark of the American Medical Association.