CPT 78121
Red cell mass multiple
CPT 78121 at a glance
- Code
- 78121
- Code type
- CPT/HCPCS
- Short descriptor
- Red cell mass multiple
- Category
- ASC Ancillary
- ASC payment status
- Payable in an ASC (ancillary)
- CMS addendum
- BB (Ancillary)
- Typical setting
- Ambulatory surgery center (POS 24) or hospital outpatient department (POS 22).
What is CPT code 78121?
CPT 78121 is a CPT/HCPCS procedure code. Its official CMS short descriptor is "Red cell mass multiple". In the ASC context it is grouped under ASC Ancillary.
Is CPT 78121 payable in an ambulatory surgery center (ASC)?
CPT 78121 is a covered ancillary service (CMS Addendum BB). Medicare reimburses it in the ASC setting when it is integral to a covered ASC surgical procedure.
Where is CPT 78121 typically performed?
Ambulatory surgery center (POS 24) or hospital outpatient department (POS 22).
Which specialties use CPT 78121?
CPT 78121 is most associated with Diagnostic Radiology.
Reference information compiled from the CMS April 2026 ASC payment addenda (AA, BB, EE). Codes, descriptors, and ASC payment status change with each CMS update. This is a coding reference, not billing, coding, or legal advice. Always verify against the current CMS addenda and individual payer policy before billing. CPT is a registered trademark of the American Medical Association.