HCPCS J2357
Omalizumab injection
HCPCS J2357 at a glance
- Code
- J2357
- Code type
- CPT/HCPCS
- Short descriptor
- Omalizumab injection
- Category
- ASC Ancillary
- ASC payment status
- Payable in an ASC (ancillary)
- CMS addendum
- BB (Ancillary)
- Typical setting
- Ambulatory surgery center (POS 24) or hospital outpatient department (POS 22).
What is HCPCS code J2357?
HCPCS J2357 is a CPT/HCPCS procedure code. Its official CMS short descriptor is "Omalizumab injection". In the ASC context it is grouped under ASC Ancillary.
Is HCPCS J2357 payable in an ambulatory surgery center (ASC)?
HCPCS J2357 is a covered ancillary service (CMS Addendum BB). Medicare reimburses it in the ASC setting when it is integral to a covered ASC surgical procedure.
Where is HCPCS J2357 typically performed?
Ambulatory surgery center (POS 24) or hospital outpatient department (POS 22).
Reference information compiled from the CMS April 2026 ASC payment addenda (AA, BB, EE). Codes, descriptors, and ASC payment status change with each CMS update. This is a coding reference, not billing, coding, or legal advice. Always verify against the current CMS addenda and individual payer policy before billing. CPT is a registered trademark of the American Medical Association.