All ASC CPT codes
Specialty Hub · Pain 62320–64999

Pain Medicine (Multidisciplinary) in the ASC and Outpatient Setting

Interventional pain medicine is one of the most procedure-dense specialties billed outside the hospital, mostly image-guided injections, nerve blocks, and ablation. The codes cluster in the CPT range 62320 to 64999, covering spinal injections like 62321 (interlaminar epidural injection, cervical or thoracic) and transforaminal epidural injections like 64483 (lumbar or sacral, single level). Many carry add-on codes for each additional level, a frequent source of under- or over-reporting.

Whether Medicare pays a code in an ASC depends on the CMS addenda. Addendum AA codes are on the ASC Covered Procedures List, meaning Medicare pays them in an ASC, while Addendum EE codes are excluded. DataLily's procedure library tracks the CPT-specific prior-authorization and documentation requirements that tend to drive denials in this specialty.

Pain Medicine (multidisciplinary) codes(1–60 of 318)

Are interventional pain procedures performed in an ASC?

Yes. Many image-guided pain procedures are performed in an ambulatory surgery center under place of service 24, and others are done in an office-based lab under place of service 11. Whether Medicare pays a specific code in an ASC depends on its CMS addendum status. Codes on Addendum AA are on the ASC Covered Procedures List and are paid in an ASC, while Addendum EE codes are excluded from ASC payment and are typically performed in the office instead.

What CPT codes does pain medicine use?

Interventional pain coding concentrates in the CPT range 62320 to 64999. This includes epidural injections such as 62321 (interlaminar cervical or thoracic), transforaminal epidural injections such as 64483 (lumbar or sacral, single level), paravertebral facet joint injections such as 64490 (cervical or thoracic, single level), and facet joint radiofrequency denervation such as 64635 (lumbar or sacral). Many of these procedures carry add-on codes reported per additional level.

Why does coding by level and region matter for pain procedures?

Epidural, facet injection, and facet denervation codes are defined by spinal region (cervical, thoracic, lumbar, or sacral) and by the number of levels treated. The base code generally covers the first level, with separate add-on codes for each additional level. Reporting the wrong region or missing the level structure is a frequent cause of denials and rework, so documentation should clearly state the region, the levels, and laterality.

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