CPT 46221
Ligation of hemorrhoid(s)
Last reviewed August 2026 · DataLily AI data team
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CPT 46221 at a glance
- Code
- 46221
- Code type
- CPT/HCPCS
- Short descriptor
- Ligation of hemorrhoid(s)
- Category
- ASC Surgical
- ASC eligibility
- ASC-eligible (surgical)
- Typical setting
- Ambulatory surgery center (POS 24); also commonly performed in an office or clinic (POS 11).
- Medicare ASC rate
- $238.33 national · 2026Q2
What is CPT code 46221?
CPT 46221 is a CPT/HCPCS procedure code for ligation of hemorrhoid(s). Its official short descriptor is "Ligation of hemorrhoid(s)". In the ASC context it is grouped under ASC Surgical.
Is CPT 46221 eligible in an ambulatory surgery center (ASC)?
CPT 46221 can be performed in a certified ambulatory surgery center.
Where is CPT 46221 typically performed?
Ambulatory surgery center (POS 24); also commonly performed in an office or clinic (POS 11).
What is the Medicare ASC payment rate for CPT 46221?
The national Medicare ASC payment rate for CPT 46221 is $238.33 (Medicare ASC Payment System, 2026Q2). This is the national, unadjusted Medicare amount; the amount an individual ambulatory surgery center is paid is adjusted for local wage index and may differ. It reflects Medicare's facility payment only and does not include the surgeon's professional fee.
Which specialties use CPT 46221?
CPT 46221 is most associated with General Surgery.
Reference information about ASC eligibility and typical procedure setting. Codes, descriptors, and ASC-eligibility status change over time. This is a coding reference, not billing, coding, or legal advice. Always verify against current guidance and individual payer policy before scheduling or billing. CPT is a registered trademark of the American Medical Association. Read the DataLily AI data methodology.