CPT 45381
Colonoscopy submucous njx
CPT 45381 at a glance
- Code
- 45381
- Code type
- CPT/HCPCS
- Short descriptor
- Colonoscopy submucous njx
- Category
- ASC Surgical
- ASC payment status
- Payable in an ASC (surgical)
- CMS addendum
- AA (Surgical)
- Typical setting
- Ambulatory surgery center (POS 24) or hospital outpatient department (POS 22).
What is CPT code 45381?
CPT 45381 is a CPT/HCPCS procedure code. Its official CMS short descriptor is "Colonoscopy submucous njx". In the ASC context it is grouped under ASC Surgical.
Is CPT 45381 payable in an ambulatory surgery center (ASC)?
CPT 45381 appears on Medicare's ASC Covered Procedures List (CMS Addendum AA), so Medicare reimburses it when the surgery is performed in a certified ambulatory surgery center.
Where is CPT 45381 typically performed?
Ambulatory surgery center (POS 24) or hospital outpatient department (POS 22).
Which specialties use CPT 45381?
CPT 45381 is most associated with Gastroenterology, General Surgery.
Reference information compiled from the CMS April 2026 ASC payment addenda (AA, BB, EE). Codes, descriptors, and ASC payment status change with each CMS update. This is a coding reference, not billing, coding, or legal advice. Always verify against the current CMS addenda and individual payer policy before billing. CPT is a registered trademark of the American Medical Association.