CPT 64721
Carpal tunnel release (neuroplasty of the median nerve at the wrist)
Last reviewed August 2026 · DataLily AI data team
What does CPT 64721 mean?
CPT 64721 reports a carpal tunnel release — neuroplasty and/or transposition of the median nerve at the carpal tunnel of the wrist. It is the standard code for open carpal tunnel surgery.
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CPT 64721 at a glance
- Code
- 64721
- Code type
- CPT/HCPCS
- Short descriptor
- Carpal tunnel surgery
- Category
- ASC Surgical
- ASC eligibility
- ASC-eligible (surgical)
- Typical setting
- Ambulatory surgery center (POS 24) or hospital outpatient department (POS 22).
- Medicare ASC rate
- $948.66 national · 2026Q2
What is CPT code 64721?
CPT 64721 reports a carpal tunnel release — neuroplasty and/or transposition of the median nerve at the carpal tunnel of the wrist. It is the standard code for open carpal tunnel surgery. Its official short descriptor is "Carpal tunnel surgery", and in the ASC context it is grouped under ASC Surgical.
Is CPT 64721 eligible in an ambulatory surgery center (ASC)?
CPT 64721 can be performed in a certified ambulatory surgery center.
Where is CPT 64721 typically performed?
Ambulatory surgery center (POS 24) or hospital outpatient department (POS 22).
What is the Medicare ASC payment rate for CPT 64721?
The national Medicare ASC payment rate for CPT 64721 is $948.66 (Medicare ASC Payment System, 2026Q2). This is the national, unadjusted Medicare amount; the amount an individual ambulatory surgery center is paid is adjusted for local wage index and may differ. It reflects Medicare's facility payment only and does not include the surgeon's professional fee.
Which specialties use CPT 64721?
CPT 64721 is most associated with Anesthesiology – Pain Medicine, Internal Medicine – Pain Medicine, Interventional Pain Medicine, Neurological Surgery, among others.
Reference information about ASC eligibility and typical procedure setting. Codes, descriptors, and ASC-eligibility status change over time. This is a coding reference, not billing, coding, or legal advice. Always verify against current guidance and individual payer policy before scheduling or billing. CPT is a registered trademark of the American Medical Association. Read the DataLily AI data methodology.